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Homepage / Testosterone Deficiency

Definition & Symptoms

Benefits of Therapy

Dosing & Administration

Safety & Tolerability

Testosterone Deficiency

Prescribing information and Adverse Event Reporting information can be found here

Definition & Symptoms

Male hypogonadism (MH), also known as testosterone deficiency, is defined by deficient testosterone production and impaired spermatogenesis by the testes.

MH is characterised biochemically by low circulating serum testosterone levels and clinically by a range of symptoms of testosterone deficiency.

MH has consequences for health and well-being beyond sexual function and contributes to male infertility.¹

Examples Of Typical Symptoms:²

Sexual symptoms e.g. low sex drive/sexual dysfunction/low sperm count.

Cardio-metabolic symptoms e.g. Increased Body Mass Index/obesity, Metabolic syndrome
Insulin resistance, pre-diabetes and type 2 diabetes.

Physical symptoms e,g. gynaecomastia, reduced muscle mass/strength,
hot flushes/sweats, sleep disturbances, Osteoporosis/height loss/low trauma fractures.

Psychological symptoms: e.g. changes in mood, diminished cognitive function.

1. Jayasena CN, Anderson RA, Llahana S, et al. Society for Endocrinology guidelines for testosterone replacement therapy in male hypogonadism. Clin Endocrinol (Oxf). 2022;96:200-219. doi:10.1111/cen.146332.2. Geoffrey Hackett, et al: BSSM Guidelines on Testosterone Deficiency World J Mens Health 2023 Jul 41(3): 508-537 https://doi.org/10.5534/wjmh.221027

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2025-03-10

Adverse events should be reported. Reporting forms and information for the UK can be found at https://yellowcard.mhra.gov.uk/ and also report using the Yellow Card app. The app is available to download from the Apple App Store, or Google Play Store and you can use your Yellow Card website account details on the app to report. Adverse events should also be reported to ADVANZ PHARMA Medical Information via telephone on +44 (0) 208 588 9131 or via e-mail at medicalinformation@advanzpharma.com

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Testosterone Deficiency

Definition & Symptoms

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